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MOUNJARO ® (tirzepatide)

Mounjaro is a weekly weight-loss injection shown in clinical trials to help people lose up to 22.5% of their body weight. Currently considered the most effective treatment of its kind,  prescribed only after a UK clinician review.
Clinician-monitored for safety and suitability
Weekly injection with gradual dose increases (titration)
Delivered discreetly by a GPhC-registered pharmacy

With Mounjaro from Weightless, become the person you’ve always wanted to be.

How Mounjaro works

Dual hormone action

Mounjaro is the first treatment to activate both GIP and GLP-1 receptors. Together, they reduce appetite, improve blood sugar control, and enhance fullness.

Supports smaller portions

By slowing how quickly food leaves your stomach, Mounjaro helps smaller meals feel satisfying. Over time, this supports steady and sustainable weight loss.

Designed for long-term change

It works best when paired with healthier eating, activity, and support tools — helping you turn short-term progress into lasting results.

How effective is Mounjaro?

Dual-action treatment delivering breakthrough results in weight loss.
Up to 22.5% body weight loss in trials
57% achieved at least 20% body weight loss
Proven results sustained beyond 72 weeks
Average loss: 15–21% across dosages
Outperformed Wegovy in head-to-head trials
Outperformed diet and exercise alone by 10x
Learn more about MOUNJARO

Dosing, side effects, and support

Starting treatment is a big step — our goal is to make it simple, safe, and supported every step of the way.
Mounjaro starts at 2.5 mg once weekly for 4 weeks, then increases to 5 mg. If appropriate, doses rise in 2.5 mg steps every ≥4 weeks to 7.5, 10, 12.5 or 15 mg.  Common side effects typically ease as doses rise gradually. Not suitable in pregnancy and with certain medical conditions—your clinician will advise.
Check your eligibility for Mounjaro
Mounjaro is generally well-tolerated, but as with all medications, side effects can occur. The most common are mild to moderate and typically improve over time as your body adjusts. They include:
Nausea
Diarrhoea
Constipation
Constipation
Reduced Hunger
Headache
It’s normal to notice side effects when starting Mounjaro or Wegovy, especially after a dose increase. If you need help managing them, open the Weightless App and connect with your care team — a clinician will respond quickly to support you.
Download the Weightless App
How it works &
Works for good
Check your eligibility
Weight loss programme that  adapts to behavior changes.
Get a clinical consult
Weight loss programme that  adapts to behavior changes.
Start on GLP-1 meds
Weight loss programme that  adapts to behavior changes.
Get ongoing support
Weight loss programme that  adapts to behavior changes.

The full toolkit for your transformation

Every element works together to keep your progress safe, consistent and sustainable over the long term.
GLP-1 Medications
Clinician-prescribed treatment to reduce appetite and aid weight loss.
Weightless App
Stay consistent with reminders, charts, and direct clinical support.
Clinical Coaching
Personalised support to keep you confident, motivated and accountable.
Healthy Meals
Nutritious, ready-to-enjoy meals supporting your weight loss journey.

Stay connected to your care, every step of the way

Every reading, check-in, and adjustment flows through the Weightless app. It helps your clinician fine-tune your dosage, your coach guide your nutrition, and you stay engaged with your progress.
Say hello to your powerful health HQ

Here's how you can expect your journey to go

Everyone’s story is different, and that’s exactly how it should be. We’re here to make sure you never walk it alone.
Doctor Consultation
28th September
Time
Place
Join Event

Adjustment and Early Appetite Changes

In the first month, your body adjusts to GLP-1 as doses increase gradually (titration). Appetite often reduces within weeks, though weight loss may be modest. Mild side effects such as nausea are common but usually ease. The main goal is safe tolerance and preparing for steady progress.

99%

users report feeling less hungry and more full.
BLOOD LABS
LIPID PROFILE
GLP-1 ACTIVE
Retest
Consult

Visible Weight Loss and Momentum

By three to six months, many see 5–10% weight loss. Reduced appetite makes smaller portions natural, and clothes begin to fit differently. Confidence grows as progress becomes visible, while healthy behaviours start to feel easier to maintain consistently with support from coaching and the app.

8/10

users report all side effects end by this stage.
on track
Hey Tabitha! Your Insight Report is here

Significant Progress and Habit Reinforcement

Weight loss really accelerates here. Energy, mobility, and wellbeing show clear improvements. Habits like mindful eating and activity feel more ingrained. Psychological benefits — stronger confidence and motivation — support long-term change, while ongoing support helps sustain progress and prevent setbacks.

93%

of patients report greater confidence after 6 months.
Alex Polishan
Elite Member
Lost 23 kg in 14 months

Long-Term Stability and Healthy Lifestyle Change

By a year, many achieve maximum benefit, typically losing 15–20% of their initial body weight. Focus shifts to maintaining progress and avoiding regain. Regular check-ins and tools help cement healthier routines, ensuring results last beyond medication and become integrated into everyday life.

Light on your waist. Lean on your wallet.

Simple, transparent pricing for expert-led weight loss.
  • Dosage: 2.5 mg
    PLANS
    Price
    Discount
    Savings
    PAYG
    £ 160
    Essentials
    £144
    10% off
    save £16
    Maintain
    £144
    10% off
    save £16
    Guided
    £136
    15% off
    save £24
  • Dosage: 5.0 mg
    PLANS
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    PAYG
    £ 195
    Essentials
    £176
    10% off
    save £20
    Maintain
    £176
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    Guided
    £166
    15% off
    save £29
  • Dosage: 7.5mg
    PLANS
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    PAYG
    £ 250
    Essentials
    £225
    10% off
    save £25
    Maintain
    £225
    10% off
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    Guided
    £213
    15% off
    save £38
  • Dosage: 10 mg
    PLANS
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    PAYG
    £ 275
    Essentials
    £248
    10% off
    save £28
    Maintain
    £248
    10% off
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    Guided
    £234
    15% off
    save £41
  • Dosage: 12.5 mg
    PLANS
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    PAYG
    £ 295
    Essentials
    £266
    10% off
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    Maintain
    £266
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    Guided
    £251
    15% off
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  • Dosage: 15 mg
    PLANS
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    PAYG
    £ 320
    Essentials
    £288
    10% off
    save £32
    Maintain
    £288
    10% off
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    Guided
    £272
    15% off
    save £48
  • Dosage: 0.25 mg
    PLANS
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    PAYG
    £ 110
    Essentials
    £99
    10% off
    save £11
    Maintain
    £99
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    Guided
    £94
    15% off
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  • Dosage: 0.5 mg
    PLANS
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    PAYG
    £ 120
    Essentials
    £108
    10% off
    save £12
    Maintain
    £108
    10% off
    save £12
    Guided
    £102
    15% off
    save £18
  • Dosage: 1 mg
    PLANS
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    PAYG
    £ 120
    Essentials
    £108
    10% off
    save £12
    Maintain
    £108
    10% off
    save £12
    Guided
    £102
    15% off
    save £18
  • Dosage: 1.7 mg
    PLANS
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    PAYG
    £ 160
    Essentials
    £144
    10% off
    save £16
    Maintain
    £144
    10% off
    save £16
    Guided
    £136
    15% off
    save £24
  • Dosage: 2.4 mg
    PLANS
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    PAYG
    £ 240
    Essentials
    £216
    10% off
    save £24
    Maintain
    £216
    10% off
    save £24
    Guided
    £204
    15% off
    save £36
  • PLANS
    Price
    Discount
    Savings
    PAYG
    £ 240
    Essentials
    £216
    10% off
    save £24
    Maintain
    £216
    10% off
    save £24
    Guided
    £204
    15% off
    save £36

Compare Wegovy vs. Mounjaro

Wegovy
mounjaro
Factor
Mechanism of action
GLP-1 receptor agonist only
Dual agonist: GLP-1 + GIP receptors
Average weight loss in trials
~15-17% over ~68 weeks
Up to ~20-22% in similar trials
Proportion losing ≥ 10%
Significant fraction (often ~50%)
Higher proportions in several trials
Maintenance evidence
Shown efficacy up to ~104 weeks in STEP-5
Trials indicate sustained results beyond 1 year
Potential benefit
Strong cardiovascular benefit in observational comparisons
Greater weight-loss effect thanks to dual receptor action

Read more about Mounjaro on our blog.

Since starting Weightless, I haven’t looked back. This is the most confident and secure I've felt in decades and I can't imagine stopping. It is truly the best!
Dorothy Weebler
Lost 21 kg in 10.5 months
Since starting Weightless, I haven’t looked back. This is the most confident and secure I've felt in decades and I can't imagine stopping. It is truly the best!
Andrew Milano
Lost 21 kg in 10.5 months
Frequently Asked Questions

Got questions about Mounjaro? We've got all the answers for you here

What is Mounjaro?
Mounjaro (Tirzepatide) is a once-weekly injectable medication, FDA-approved under the brand name Mounjaro to treat type 2 diabetes as well as under the brand name Zepbound for weight loss. Both medications are administered via a once-weekly injection using a pre-filled single-dose pen.
How does tirzepatide work?
Tirzepatide works similarly to other GLP-1 medications, however, tirzepatide differs from the other medications in that it is a dual-action GLP-1 (short for glucagon-like peptide 1) and GIP (short for glucose-dependent insulinotropic polypeptide) medication. This means that it works by mimicking the action of both the GLP-1 and GIP hormones, which help regulate your metabolism. In doing so, tirzepatide makes you feel fuller faster and for longer. It also communicates with the part of your brain in charge of hunger and satiety, helping you regulate how much you eat. When combined with an appropriate diet and exercise, this makes tirzepatide an effective treatment for weight loss.
Will I get a refund if I don't lose at least 20 pounds of weight?
Tirzepatide comes in doses of 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, and 15 mg. Similar to other GLP-1 medications, tirzepatide dosing gradually increases. If prescribed, you’ll start on the lowest dose (2.5 mg) for the first four weeks, and then work with your provider to slowly increase your dose every four weeks until you reach a steady dose that works best for you.
How do you take tirzepatide?
Tirzepatide is a once-weekly injection that comes in a pre-filled, single-dose pen. If prescribed, you’ll receive detailed instructions from your Weightless support team on how to inject it in your stomach, arm, or thigh.

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